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Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells

A subset of environmental chemicals acts as “obesogens” as they increase adipose mass and lipid content in livers of treated rodents. One of the most studied class of obesogens are the tin-containing chemicals that have as a central moiety tributyltin (TBT), which bind and activate two nuclear hormo...

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Detalles Bibliográficos
Autores principales: Stossi, Fabio, Dandekar, Radhika D., Johnson, Hannah, Lavere, Philip, Foulds, Charles E., Mancini, Maureen G., Mancini, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844554/
https://www.ncbi.nlm.nih.gov/pubmed/31710612
http://dx.doi.org/10.1371/journal.pone.0224405