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Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells
A subset of environmental chemicals acts as “obesogens” as they increase adipose mass and lipid content in livers of treated rodents. One of the most studied class of obesogens are the tin-containing chemicals that have as a central moiety tributyltin (TBT), which bind and activate two nuclear hormo...
Autores principales: | Stossi, Fabio, Dandekar, Radhika D., Johnson, Hannah, Lavere, Philip, Foulds, Charles E., Mancini, Maureen G., Mancini, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844554/ https://www.ncbi.nlm.nih.gov/pubmed/31710612 http://dx.doi.org/10.1371/journal.pone.0224405 |
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