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Paracrine signalling of AGR2 stimulates RhoA function in fibroblasts and modulates cell elongation and migration
The most prominent cancer-associated fibroblasts (CAFs) in tumor stroma is known to form a protective structure to support tumor growth. Anterior gradient-2 (AGR2), a tumor secretory protein is believed to play a pivotal role during tumor microenvironment (TME) development. Here, we report that extr...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844563/ https://www.ncbi.nlm.nih.gov/pubmed/31710263 http://dx.doi.org/10.1080/19336918.2019.1685928 |