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Identification of the Selenoprotein S Positive UGA Recoding (SPUR) element and its position-dependent activity

Selenoproteins are a unique class of proteins that contain the 21(st) amino acid, selenocysteine (Sec). Addition of Sec into a protein is achieved by recoding of the UGA stop codon. All 25 mammalian selenoprotein mRNAs possess a 3′ UTR stem-loop structure, the Selenocysteine Insertion Sequence (SECI...

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Detalles Bibliográficos
Autores principales: Cockman, Eric M., Narayan, Vivek, Willard, Belinda, Shetty, Sumangala P., Copeland, Paul R., Driscoll, Donna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844570/
https://www.ncbi.nlm.nih.gov/pubmed/31432740
http://dx.doi.org/10.1080/15476286.2019.1653681