The VEGF-A exon 8 splicing-sensitive fluorescent reporter mouse is a novel tool to assess the effects of splicing regulatory compounds in vivo

Vascular endothelial growth factor (VEGF)-A is differentially spliced to give two functionally different isoform families; pro-angiogenic, pro-permeability VEGF-A(xxx) and anti-angiogenic, anti-permeability VEGF-A(xxx)b. VEGF-A splicing is dysregulated in several pathologies, including cancer, diabe...

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Detalles Bibliográficos
Autores principales: Stevens, M., Star, E., Lee, M., Innes, E., Li, L., Bowler, E., Harper, S., Bates, D. O., Oltean, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844573/
https://www.ncbi.nlm.nih.gov/pubmed/31432737
http://dx.doi.org/10.1080/15476286.2019.1652522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844573/
https://www.ncbi.nlm.nih.gov/pubmed/31432737
http://dx.doi.org/10.1080/15476286.2019.1652522

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