Cargando…
The VEGF-A exon 8 splicing-sensitive fluorescent reporter mouse is a novel tool to assess the effects of splicing regulatory compounds in vivo
Vascular endothelial growth factor (VEGF)-A is differentially spliced to give two functionally different isoform families; pro-angiogenic, pro-permeability VEGF-A(xxx) and anti-angiogenic, anti-permeability VEGF-A(xxx)b. VEGF-A splicing is dysregulated in several pathologies, including cancer, diabe...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844573/ https://www.ncbi.nlm.nih.gov/pubmed/31432737 http://dx.doi.org/10.1080/15476286.2019.1652522 |