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TNFα-induced Up-regulation of Ascl2 Affects the Differentiation and Proliferation of Neural Stem Cells

The molecular mediators underlying the effects of inflammation on neural stem cells (NSCs) are not fully characterized. In this study, we identified Ascl2 as a downstream basic helix-loop-helix (bHLH) transcription factor in NSCs following exposure to TNFα. Under normal conditions, Ascl2 expression...

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Detalles Bibliográficos
Autores principales: Liu, Zhongfeng, Wang, Xuan, Jiang, Kewen, Ji, Xunming, Zhang, Y. Alex, Chen, Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844591/
https://www.ncbi.nlm.nih.gov/pubmed/31788333
http://dx.doi.org/10.14336/AD.2018.1028