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TNFα-induced Up-regulation of Ascl2 Affects the Differentiation and Proliferation of Neural Stem Cells
The molecular mediators underlying the effects of inflammation on neural stem cells (NSCs) are not fully characterized. In this study, we identified Ascl2 as a downstream basic helix-loop-helix (bHLH) transcription factor in NSCs following exposure to TNFα. Under normal conditions, Ascl2 expression...
Autores principales: | Liu, Zhongfeng, Wang, Xuan, Jiang, Kewen, Ji, Xunming, Zhang, Y. Alex, Chen, Zhiguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JKL International LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844591/ https://www.ncbi.nlm.nih.gov/pubmed/31788333 http://dx.doi.org/10.14336/AD.2018.1028 |
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