Verapamil Ameliorates Motor Neuron Degeneration and Improves Lifespan in the SOD1(G93A) Mouse Model of ALS by Enhancing Autophagic Flux

Amyotrophic lateral sclerosis (ALS) is a progressive, paralytic disorder caused by selective degeneration of motor neurons in the brain and spinal cord. Our previous studies indicated that abnormal protein aggregation and dysfunctional autophagic flux might contribute to the disease pathogenesis. In...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaojie, Chen, Sheng, Lu, Kaili, Wang, Feng, Deng, Jiangshan, Xu, Zhouwei, Wang, Xiuzhe, Zhou, Qinming, Le, Weidong, Zhao, Yuwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2019
Materias:
Orginal Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844595/
https://www.ncbi.nlm.nih.gov/pubmed/31788329
http://dx.doi.org/10.14336/AD.2019.0228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844595/
https://www.ncbi.nlm.nih.gov/pubmed/31788329
http://dx.doi.org/10.14336/AD.2019.0228

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