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TROP2 increases growth and metastasis of human oral squamous cell carcinoma through activation of the PI3K/Akt signaling pathway

Most malignant neoplasms of the oral cavity are oral squamous cell carcinoma (OSCC), which is a type of highly malignant tumor with a propensity for forming distant metastases. Trophoblast cell surface antigen 2 (TROP2) is a transmembrane protein that is overexpressed in several types of tumor cells...

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Detalles Bibliográficos
Autores principales: Tang, Genxiong, Tang, Qi, Jia, Lizhou, Chen, Yuan, Lin, Liangyuan, Kuai, Xingwang, Gong, Aixiu, Feng, Zhengqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844621/
https://www.ncbi.nlm.nih.gov/pubmed/31638186
http://dx.doi.org/10.3892/ijmm.2019.4378