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Upregulation of sphingosine kinase 1 contributes to ventilator-associated lung injury in a two-hit model
Ventilator-associated lung injury (VALI) remains a significant medical problem in intensive care units. The present study aimed to investigate the role of sphingosine kinase 1 (SPHK1) in VALI using a two-hit model and explore the potential underlying molecular mechanism. Mice were divided into five...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844625/ https://www.ncbi.nlm.nih.gov/pubmed/31638192 http://dx.doi.org/10.3892/ijmm.2019.4379 |