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Role and mechanisms of action of microRNA-21 as regards the regulation of the WNT/β-catenin signaling pathway in the pathogenesis of non-alcoholic fatty liver disease

The aim of the present study was to investigate the role of microRNA-21 (miR-21) in regulating the classical WNT/β-catenin signaling pathway by targeting low-density lipoprotein-related receptor 6 (LRP6) in non-alcoholic fatty liver disease (NAFLD). For this purpose, we established a NAFLD model by...

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Detalles Bibliográficos
Autores principales: Wang, Xiu-Mei, Wang, Xiao-Yi, Huang, Yu-Mei, Chen, Xia, Lü, Mu-Han, Shi, Lei, Li, Chang-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844630/
https://www.ncbi.nlm.nih.gov/pubmed/31638173
http://dx.doi.org/10.3892/ijmm.2019.4375