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Bioinformatics analysis of Ras homologue enriched in the striatum, a potential target for Huntington's disease therapy

Huntington's disease (HD) is a lethal neurodegenerative disorder for which no cure is available yet. It is caused by abnormal expansion of a CAG triplet in the gene encoding the huntingtin protein (Htt), with consequent expansion of a polyglutamine repeat in mutated Htt (mHtt). This makes mHtt...

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Detalles Bibliográficos
Autores principales: Carbo, Miriam, Brandi, Valentina, Pascarella, Gianmarco, Staid, David Sasah, Colotti, Gianni, Polticelli, Fabio, Ilari, Andrea, Morea, Veronica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844632/
https://www.ncbi.nlm.nih.gov/pubmed/31638189
http://dx.doi.org/10.3892/ijmm.2019.4373