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Tacrolimus increases the expression level of the chemokine receptor CXCR2 to promote renal fibrosis progression

Tacrolimus is one of the most used and effective immunosuppressive agents currently available in the clinic; however, its use is limited by nephrotoxicity, which is the main secondary effect of this drug. The mechanisms underlying tacrolimus-induced nephrotoxicity remain unknown. The present study a...

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Detalles Bibliográficos
Autores principales: Wang, Dongdong, Chen, Xiao, Fu, Meng, Xu, Hong, Li, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844638/
https://www.ncbi.nlm.nih.gov/pubmed/31638188
http://dx.doi.org/10.3892/ijmm.2019.4368