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Combination of In Vivo [(123)I]FP-CIT SPECT and Microdialysis Reveals an Antipsychotic Drug Haloperidol-induced Synaptic Dopamine Availability in the Rat Midbrain and Striatum

Synaptic dopamine (DA) is mainly regulated by the presynaptic DA transporter (DAT). Single-photon emission computerized tomography (SPECT) with the DAT radiotracer [(123)I]FP-CIT assesses changes in synaptic DA availability when endogenous DA displaces [(123)I]FP-CIT or competes for DAT. Here, we in...

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Detalles Bibliográficos
Autores principales: Park, So Hyeon, Song, Yoo Sung, Moon, Byung Seok, Lee, Byung Chul, Park, Hyun Soo, Kim, Sang Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844836/
https://www.ncbi.nlm.nih.gov/pubmed/31698552
http://dx.doi.org/10.5607/en.2019.28.5.602