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IMPROVED HEALTHSPAN AND LIFESPAN WITH LATE ONSET PHARMACOLOGICAL OR DIETARY INTERVENTIONS IN MICE

While late-onset dietary (e.g. calorie restriction) or pharmacological (e.g. rapamycin) interventions can extend longevity in rodents, whether or not they can be used to reverse or forestall onset of aging-related symptoms (i.e. frailty) remains untested. Here, we employed methionine restriction (MR...

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Detalles Bibliográficos
Autores principales: Mitchell, Sarah, MacArthur, Michael, Kane, Alice, Torrence, Margaret, Manning, Brendan, mItchell, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844886/
http://dx.doi.org/10.1093/geroni/igz038.3207