Cargando…
MITOCHONDRIAL DNA VARIANT C2639T IS AN APOE4 RESILIENCE FACTOR
The APOE4 allele is the greatest genetic risk factor for sporadic Alzheimer’s disease, yet select APOE4 carriers remain cognitively intact and become centenarians due to unclear reasons. In order to identify resilience genes for APOE4 carriers, we (1) sequenced whole mitochondrial DNA in a centenari...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845116/ http://dx.doi.org/10.1093/geroni/igz038.3417 |