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MITOCHONDRIAL DNA VARIANT C2639T IS AN APOE4 RESILIENCE FACTOR

The APOE4 allele is the greatest genetic risk factor for sporadic Alzheimer’s disease, yet select APOE4 carriers remain cognitively intact and become centenarians due to unclear reasons. In order to identify resilience genes for APOE4 carriers, we (1) sequenced whole mitochondrial DNA in a centenari...

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Detalles Bibliográficos
Autores principales:	Miller, Brendan, Kim, Su Jeong, Wan, Junxiang, Mehta, Hemal H, Yen, Kelvin, Cohen, Pinchas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Session Lb2570 (Late Breaking Poster)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845116/ http://dx.doi.org/10.1093/geroni/igz038.3417

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