ALTERED TRYPTOPHAN DEGRADATION LINKS CHRONIC INFLAMMATION TO FUNCTIONAL DECLINE & FRAILTY IN MICE AND HUMANS

Chronic inflammation is associated with frailty and functional decline in older adults but the molecular mechanisms of this linkage are not well understood. We sought to examine metabolic and physiologic states associated with aging and frailty by analyzing the composition of metabolites in the bloo...

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Detalles Bibliográficos
Autores principales: Westbrook, Reyhan, Chung, Tae, Lovett, Jacqueline, Ward, Chris, Khadeer, Mohammed, Moaddel, Ruin, Walston, Jeremy, Abadir, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Session Lb3620 (Late Breaking Poster)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845122/
http://dx.doi.org/10.1093/geroni/igz038.3473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845122/
http://dx.doi.org/10.1093/geroni/igz038.3473

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