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HOW MANY MOLECULAR MECHANISMS MUST BE ALTERED SIMULTANEOUSLY TO SLOW AGING AND EXTEND LIFESPAN?

Most anti-aging therapeutics are designed to target single molecules, single molecular mechanisms, or single cell types. Yet, to produce a substantial lifespan extension, these interventions would need to act promiscuously and delay the onset of many or all causes of death. In invertebrate models, s...

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Detalles Bibliográficos
Autor principal: Stroustrup, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845152/
http://dx.doi.org/10.1093/geroni/igz038.754