TARGETING THE NLRP3 INFLAMMASOME IN MECHANISMS OF SLEEP DEPRIVATION-INDUCED NEUROINFLAMMATION

The purpose of this study was to determine if inhibitors of innate immunity in microglia could attenuate sleep deprivation (SD)-induced psychological impairment, which involve the assembly and activation of the NLRP3 inflammasome. In the study, CD-1 mice were immune-primed with chronic corticosteron...

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Detalles Bibliográficos
Autores principales: Smith, Chad, Trageser, Kyle, Pasinetti, Giulio M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845347/
http://dx.doi.org/10.1093/geroni/igz038.360