Cargando…
TARGETING THE NLRP3 INFLAMMASOME IN MECHANISMS OF SLEEP DEPRIVATION-INDUCED NEUROINFLAMMATION
The purpose of this study was to determine if inhibitors of innate immunity in microglia could attenuate sleep deprivation (SD)-induced psychological impairment, which involve the assembly and activation of the NLRP3 inflammasome. In the study, CD-1 mice were immune-primed with chronic corticosteron...
Autores principales: | Smith, Chad, Trageser, Kyle, Pasinetti, Giulio M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845347/ http://dx.doi.org/10.1093/geroni/igz038.360 |
Ejemplares similares
-
PRIMING OF MICROGLIA ACTIVITY INCREASES SUSCEPTIBILITY TO DEPRESSION-LIKE BEHAVIORS
por: Frolinger, Tal, et al.
Publicado: (2019) -
Anxiolytic effects of NLRP3 inflammasome inhibition in a model of chronic sleep deprivation
por: Smith, Chad, et al.
Publicado: (2021) -
TAU-INDUCED ASTROCYTE SENESCENCE: A NOVEL MECHANISM FOR NEURONAL DYSFUNCTION IN ALZHEIMER’S DISEASE
por: Olson, Angela, et al.
Publicado: (2019) -
THE CEREBELLUM MAY MITIGATE OBESITY-DRIVEN COGNITIVE IMPAIRMENT IN LATE LIFE
por: Garbarino, Valentina R, et al.
Publicado: (2019) -
NOVEL GAMMA-SECRETASE MODULATOR REGULATES APP PROCESSING AND INFLAMMATORY RESPONSES IN NPM-EXPOSED MICE
por: D'Agostino, Carla, et al.
Publicado: (2019)