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SENESCENCE SECRETOME: BIOMARKERS OF BIOLOGICAL AGING AND POSTOPERATIVE OUTCOMES

Senescent cells drive age-related tissue dysfunction through their potent secretome, termed the senescence associated secretory phenotype (SASP). Circulating concentrations of SASP factors may reflect biological age and serve as clinically useful biomarkers of surgical risk and ultimately, surrogate...

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Detalles Bibliográficos
Autores principales: Schafer, Marissa, Zhang, Xu, Kumar, Amanika, White, Thomas, Atkinson, Elizabeth, Burning, Michelle, LeBrasseur, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845427/
http://dx.doi.org/10.1093/geroni/igz038.370