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INTERACTIONS BETWEEN GENES FROM AGING-RELATED PATHWAYS: IMPACT ON HUMAN LONGEVITY

Role of genetic interactions (GxG) in human longevity remains poorly understood. We hypothesized that GxG between genes from biologically connected pathways involved in aging may impact longevity. To test this hypothesis, we selected 53 candidate genes from the aging-related pathways (IGF-1/AKT/FOXO...

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Detalles Bibliográficos
Autores principales: Ukraintseva, Svetlana, Duan, Matt, Wu, Deqing, Arbeev, Konstantin, Kulminski, Alexander, Zmuda, Joseph M, Christensen, Kaare, Yashin, Anatoliy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845781/
http://dx.doi.org/10.1093/geroni/igz038.3284