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INTERACTIONS BETWEEN GENES FROM AGING-RELATED PATHWAYS: IMPACT ON HUMAN LONGEVITY
Role of genetic interactions (GxG) in human longevity remains poorly understood. We hypothesized that GxG between genes from biologically connected pathways involved in aging may impact longevity. To test this hypothesis, we selected 53 candidate genes from the aging-related pathways (IGF-1/AKT/FOXO...
Autores principales: | Ukraintseva, Svetlana, Duan, Matt, Wu, Deqing, Arbeev, Konstantin, Kulminski, Alexander, Zmuda, Joseph M, Christensen, Kaare, Yashin, Anatoliy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845781/ http://dx.doi.org/10.1093/geroni/igz038.3284 |
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