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LOSS OF HYPOXIA SIGNALING LIMITS SKELETAL MUSCLE RESPONSE TO AEROBIC EXERCISE IN AGING

Skeletal muscle function declines with aging. Physical activity improves muscle function, but may require upregulation of the hypoxia signalling pathway. In this study, we examine the effect of exercise on muscle function in young and old mice and explore the role of hypoxia pathway in mediating exe...

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Detalles Bibliográficos
Autores principales: Endo, Yori, Li, Bin, Udeh, Kodi, Panayi, Adriana C, Neppl, Ron, Sinha, Indranil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845883/
http://dx.doi.org/10.1093/geroni/igz038.342