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Effect of adenovirus-mediated overexpression of PTEN on brain oxidative damage and neuroinflammation in a rat kindling model of epilepsy

BACKGROUND: Epilepsy is a chronic and severe neurological disorder. Phosphatase and tensin homolog deleted on chromosome ten (PTEN)-deficient mice exhibit learning and memory deficits and spontaneous epilepsy. The aim of this study was to investigate the role of PTEN in brain oxidative damage and ne...

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Detalles Bibliográficos
Autores principales: Wu, Zhi-Sheng, Huang, Wen-Li, Gong, Shu-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6846256/
https://www.ncbi.nlm.nih.gov/pubmed/31658159
http://dx.doi.org/10.1097/CM9.0000000000000496