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Robust gene expression control in human cells with a novel universal TetR aptamer splicing module
Fine-tuning of gene expression is desirable for a wide range of applications in synthetic biology. In this context, RNA regulatory devices provide a powerful and highly functional tool. We developed a versatile, robust and reversible device to control gene expression by splicing regulation in human...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6846422/ https://www.ncbi.nlm.nih.gov/pubmed/31504742 http://dx.doi.org/10.1093/nar/gkz753 |