Cargando…
Robust gene expression control in human cells with a novel universal TetR aptamer splicing module
Fine-tuning of gene expression is desirable for a wide range of applications in synthetic biology. In this context, RNA regulatory devices provide a powerful and highly functional tool. We developed a versatile, robust and reversible device to control gene expression by splicing regulation in human...
Autores principales: | Mol, Adam A, Groher, Florian, Schreiber, Britta, Rühmkorff, Ciaran, Suess, Beatrix |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6846422/ https://www.ncbi.nlm.nih.gov/pubmed/31504742 http://dx.doi.org/10.1093/nar/gkz753 |
Ejemplares similares
-
Inducible nuclear import by TetR aptamer-controlled 3′ splice site selection
por: Mol, Adam A., et al.
Publicado: (2021) -
The complex formed between a synthetic RNA aptamer and the transcription repressor TetR is a structural and functional twin of the operator DNA–TetR regulator complex
por: Grau, Florian C, et al.
Publicado: (2020) -
Design and implementation of a synthetic pre-miR switch for controlling miRNA biogenesis in mammals
por: Atanasov, Janina, et al.
Publicado: (2017) -
Redesigned TetR-Aptamer System To Control Gene Expression in Plasmodium falciparum
por: Rajaram, Krithika, et al.
Publicado: (2020) -
A small, portable RNA device for the control of exon skipping in mammalian cells
por: Vogel, Marc, et al.
Publicado: (2018)