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EFFECT OF TLR4 INHIBITION IN FAT-INDUCED INSULIN RESISTANCE IN HUMAN SUBJECTS

Older and obese subjects have increased levels of free fatty acids (FFA) in plasma that may mediate the inflammation and insulin resistance seen in these individuals. Data generated mostly in cells and rodents suggest that toll like receptor 4 (TLR4) mediates the inflammatory and insulin resistant s...

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Detalles Bibliográficos
Autores principales: Liang, Hanyu, Sathavarodom, Nattapol, Colmenares, Claudia, Ganapathy, Vinutha, Orsak, Beverly, Musi, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6846838/
http://dx.doi.org/10.1093/geroni/igz038.393