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A general LC-MS-based RNA sequencing method for direct analysis of multiple-base modifications in RNA mixtures
A complete understanding of the structural and functional potential of RNA requires understanding of chemical modifications and non-canonical bases; this in turn requires advances in current sequencing methods to be able to sequence not only canonical ribonucleotides, but at the same time directly s...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6847078/ https://www.ncbi.nlm.nih.gov/pubmed/31504795 http://dx.doi.org/10.1093/nar/gkz731 |