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Detection of internal N7-methylguanosine (m(7)G) RNA modifications by mutational profiling sequencing

Methylation of guanosine on position N7 (m(7)G) on internal RNA positions has been found in all domains of life and have been implicated in human disease. Here, we present m(7)G Mutational Profiling sequencing (m(7)G-MaP-seq), which allows high throughput detection of m(7)G modifications at nucleoti...

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Detalles Bibliográficos
Autores principales: Enroth, Christel, Poulsen, Line Dahl, Iversen, Søren, Kirpekar, Finn, Albrechtsen, Anders, Vinther, Jeppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6847341/
https://www.ncbi.nlm.nih.gov/pubmed/31504776
http://dx.doi.org/10.1093/nar/gkz736