CSB interacts with BRCA1 in late S/G2 to promote MRN- and CtIP-mediated DNA end resection

CSB, a member of the SWI2/SNF2 superfamily, has been implicated in evicting histones to promote the DSB pathway choice towards homologous recombination (HR) repair. However, how CSB promotes HR repair remains poorly characterized. Here we demonstrate that CSB interacts with both MRE11/RAD50/NBS1 (MR...

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Detalles Bibliográficos
Autores principales: Batenburg, Nicole L, Walker, John R, Coulombe, Yan, Sherker, Alana, Masson, Jean-Yves, Zhu, Xu-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6847465/
https://www.ncbi.nlm.nih.gov/pubmed/31501894
http://dx.doi.org/10.1093/nar/gkz784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6847465/
https://www.ncbi.nlm.nih.gov/pubmed/31501894
http://dx.doi.org/10.1093/nar/gkz784

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