Cargando…

CSB interacts with BRCA1 in late S/G2 to promote MRN- and CtIP-mediated DNA end resection

CSB, a member of the SWI2/SNF2 superfamily, has been implicated in evicting histones to promote the DSB pathway choice towards homologous recombination (HR) repair. However, how CSB promotes HR repair remains poorly characterized. Here we demonstrate that CSB interacts with both MRE11/RAD50/NBS1 (MR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Batenburg, Nicole L, Walker, John R, Coulombe, Yan, Sherker, Alana, Masson, Jean-Yves, Zhu, Xu-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6847465/ https://www.ncbi.nlm.nih.gov/pubmed/31501894 http://dx.doi.org/10.1093/nar/gkz784

Ejemplares similares

CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1
por: Quennet, Verena, et al.
Publicado: (2011)

SUMOylation mediates CtIP’s functions in DNA end resection and replication fork protection
por: Locke, Andrew J, et al.
Publicado: (2021)

The internal region of CtIP negatively regulates DNA end resection
por: Howard, Sean Michael, et al.
Publicado: (2020)

NF-κB regulates DNA double-strand break repair in conjunction with BRCA1–CtIP complexes
por: Volcic, Meta, et al.
Publicado: (2012)

CtIP-BRCA1 complex and MRE11 maintain replication forks in the presence of chain terminating nucleoside analogs
por: Mohiuddin, Mohiuddin, et al.
Publicado: (2019)

NBS1-CtIP–mediated DNA end resection suppresses cGAS binding to micronuclei
por: Abdisalaam, Salim, et al.
Publicado: (2022)

SIAH2 regulates DNA end resection and replication fork recovery by promoting CtIP ubiquitination
por: Jeong, Seo-Yeon, et al.
Publicado: (2022)

Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice
por: Jimeno, Sonia, et al.
Publicado: (2015)

PLK1 targets CtIP to promote microhomology-mediated end joining
por: Wang, Hailong, et al.
Publicado: (2018)

Cockayne syndrome group B protein regulates fork restart, fork progression and MRE11-dependent fork degradation in BRCA1/2-deficient cells
por: Batenburg, Nicole L, et al.
Publicado: (2021)

And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenance
por: Chen, Yali, et al.
Publicado: (2017)

CTCF cooperates with CtIP to drive homologous recombination repair of double-strand breaks
por: Hwang, Soon Young, et al.
Publicado: (2019)

SERBP1 affects homologous recombination-mediated DNA repair by regulation of CtIP translation during S phase
por: Ahn, Jang-Won, et al.
Publicado: (2015)

CSB interacts with SNM1A and promotes DNA interstrand crosslink processing
por: Iyama, Teruaki, et al.
Publicado: (2015)

Interactions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantum
por: Genois, Marie-Michelle, et al.
Publicado: (2012)

Nucleotide excision repair in Human cell lines lacking both XPC and CSB proteins
por: Lindsey-Boltz, Laura A, et al.
Publicado: (2023)

Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks
por: Cheng, Qiao, et al.
Publicado: (2011)

The MRN complex promotes DNA repair by homologous recombination and restrains antigenic variation in African trypanosomes
por: Mehnert, Ann-Kathrin, et al.
Publicado: (2021)

The transcription-coupled DNA repair-initiating protein CSB promotes XRCC1 recruitment to oxidative DNA damage
por: Menoni, Hervé, et al.
Publicado: (2018)

An R-loop-initiated CSB–RAD52–POLD3 pathway suppresses ROS-induced telomeric DNA breaks
por: Tan, Jun, et al.
Publicado: (2020)

hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex
por: Richard, Derek J., et al.
Publicado: (2011)

The CSB chromatin remodeler regulates PARP1- and PARP2-mediated single-strand break repair at actively transcribed DNA regions
por: Bilkis, Rabeya, et al.
Publicado: (2023)

hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity
por: Richard, Derek J., et al.
Publicado: (2011)

ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance
por: O’Sullivan, Julia, et al.
Publicado: (2023)

MRN, CtIP, and BRCA1 mediate repair of topoisomerase II–DNA adducts
por: Aparicio, Tomas, et al.
Publicado: (2016)

The identification of FANCD2 DNA binding domains reveals nuclear localization sequences
por: Niraj, Joshi, et al.
Publicado: (2017)

Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection
por: Kakarougkas, Andreas, et al.
Publicado: (2013)

Targeting BRCA1- and BRCA2-deficient cells with RAD52 small molecule inhibitors
por: Huang, Fei, et al.
Publicado: (2016)

RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells
por: Krishnan, Rehna, et al.
Publicado: (2023)

PALB2 self-interaction controls homologous recombination
por: Buisson, Rémi, et al.
Publicado: (2012)

DSS1 and ssDNA regulate oligomerization of BRCA2
por: Le, Hang Phuong, et al.
Publicado: (2020)

LKB1 preserves genome integrity by stimulating BRCA1 expression
por: Gupta, Romi, et al.
Publicado: (2015)

Antagonism between BRCA2 and FIGL1 regulates homologous recombination
por: Kumar, Rajeev, et al.
Publicado: (2019)

Estimation of the RNU2 macrosatellite mutation rate by BRCA1 mutation tracing
por: Tessereau, Chloé, et al.
Publicado: (2014)

BRCA1 modulates the autophosphorylation status of DNA-PKcs in S phase of the cell cycle
por: Davis, Anthony J., et al.
Publicado: (2014)

Conformational flexibility and oligomerization of BRCA2 regions induced by RAD51 interaction
por: Sidhu, Arshdeep, et al.
Publicado: (2020)

Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair
por: Li, Niu, et al.
Publicado: (2020)

Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers
por: Patel, Parasvi S, et al.
Publicado: (2023)

Contributions of the RAD51 N-terminal domain to BRCA2-RAD51 interaction
por: Subramanyam, Shyamal, et al.
Publicado: (2013)

Architectural plasticity of human BRCA2–RAD51 complexes in DNA break repair
por: Sánchez, Humberto, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_7dkmvq6uokr0kd9d9n90iuqj96