Phosphorylation of Drosophila CENP-A on serine 20 regulates protein turn-over and centromere-specific loading

Centromeres are specialized chromosomal regions epigenetically defined by the presence of the histone H3 variant CENP-A. CENP-A is required for kinetochore formation which is essential for chromosome segregation during mitosis. Spatial restriction of CENP-A to the centromere is tightly controlled. I...

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Detalles Bibliográficos
Autores principales: Huang, Anming, Kremser, Leopold, Schuler, Fabian, Wilflingseder, Doris, Lindner, Herbert, Geley, Stephan, Lusser, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6847487/
https://www.ncbi.nlm.nih.gov/pubmed/31535131
http://dx.doi.org/10.1093/nar/gkz809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6847487/
https://www.ncbi.nlm.nih.gov/pubmed/31535131
http://dx.doi.org/10.1093/nar/gkz809

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