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Phosphorylation of Drosophila CENP-A on serine 20 regulates protein turn-over and centromere-specific loading
Centromeres are specialized chromosomal regions epigenetically defined by the presence of the histone H3 variant CENP-A. CENP-A is required for kinetochore formation which is essential for chromosome segregation during mitosis. Spatial restriction of CENP-A to the centromere is tightly controlled. I...
Autores principales: | Huang, Anming, Kremser, Leopold, Schuler, Fabian, Wilflingseder, Doris, Lindner, Herbert, Geley, Stephan, Lusser, Alexandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6847487/ https://www.ncbi.nlm.nih.gov/pubmed/31535131 http://dx.doi.org/10.1093/nar/gkz809 |
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