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Oral antenatal corticosteroids evaluated in fetal sheep

BACKGROUND: The use of antenatal corticosteroids (ACS) in low-resource environments is sporadic. Further, drug choice, dose, and route of ACS are not optimized. We report the pharmacokinetics and pharmacodynamics of oral dosing of ACS using a preterm sheep model. METHODS: We measured pharmacokinetic...

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Detalles Bibliográficos
Autores principales: Schmidt, Augusto F., Jobe, Alan H., Kannan, Paranthaman S., Bridges, James P., Newnham, John P., Saito, Masatoshi, Usuda, Haruo, Kumagai, Yusaku, Fee, Erin L., Clarke, Michael, Kemp, Matthew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848022/
https://www.ncbi.nlm.nih.gov/pubmed/31365919
http://dx.doi.org/10.1038/s41390-019-0519-0