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The Immunogenicity and Anti-tumor Efficacy of a Rationally Designed Neoantigen Vaccine for B16F10 Mouse Melanoma

Tumor neoantigens are ideal targets for cancer immunotherapy as they are recognized by host immune system as foreigners and can elicit tumor-specific immune responses. However, existing strategies utilizing RNA or long peptides for the neoantigen vaccines render limited immune responses since only 2...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Lin, Zhibing, Wan, Yuhua, Cai, Huaman, Deng, Li, Li, Rongxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848027/
https://www.ncbi.nlm.nih.gov/pubmed/31749795
http://dx.doi.org/10.3389/fimmu.2019.02472