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A gene regulatory network to control EMT programs in development and disease

The Epithelial to Mesenchymal Transition (EMT) regulates cell plasticity during embryonic development and in disease. It is dynamically orchestrated by transcription factors (EMT-TFs), including Snail, Zeb, Twist and Prrx, all activated by TGF-β among other signals. Here we find that Snail1 and Prrx...

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Detalles Bibliográficos
Autores principales: Fazilaty, Hassan, Rago, Luciano, Kass Youssef, Khalil, Ocaña, Oscar H., Garcia-Asencio, Francisco, Arcas, Aida, Galceran, Juan, Nieto, M. Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848104/
https://www.ncbi.nlm.nih.gov/pubmed/31712603
http://dx.doi.org/10.1038/s41467-019-13091-8