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A gene regulatory network to control EMT programs in development and disease
The Epithelial to Mesenchymal Transition (EMT) regulates cell plasticity during embryonic development and in disease. It is dynamically orchestrated by transcription factors (EMT-TFs), including Snail, Zeb, Twist and Prrx, all activated by TGF-β among other signals. Here we find that Snail1 and Prrx...
Autores principales: | Fazilaty, Hassan, Rago, Luciano, Kass Youssef, Khalil, Ocaña, Oscar H., Garcia-Asencio, Francisco, Arcas, Aida, Galceran, Juan, Nieto, M. Angela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848104/ https://www.ncbi.nlm.nih.gov/pubmed/31712603 http://dx.doi.org/10.1038/s41467-019-13091-8 |
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