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Pioglitazone Modulates the Vascular Contractility in Hypertension by Interference with ET-1 Pathway

Endothelin-1 (ET-1) is an important modulator of the vascular tone and a proinflammatory molecule that contributes to the vascular damage observed in hypertension. Peroxisome-proliferator activated receptors-γ (PPARγ) agonists show cardioprotective properties by decreasing inflammatory molecules suc...

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Detalles Bibliográficos
Autores principales: Palacios-Ramírez, Roberto, Hernanz, Raquel, Martín, Angela, Pérez-Girón, José V., Barrús, María T., González-Carnicero, Zoe, Aguado, Andrea, Jaisser, Frederic, Briones, Ana M., Salaices, Mercedes, Alonso, María J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848177/
https://www.ncbi.nlm.nih.gov/pubmed/31712626
http://dx.doi.org/10.1038/s41598-019-52839-6