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Pioglitazone Modulates the Vascular Contractility in Hypertension by Interference with ET-1 Pathway
Endothelin-1 (ET-1) is an important modulator of the vascular tone and a proinflammatory molecule that contributes to the vascular damage observed in hypertension. Peroxisome-proliferator activated receptors-γ (PPARγ) agonists show cardioprotective properties by decreasing inflammatory molecules suc...
Autores principales: | Palacios-Ramírez, Roberto, Hernanz, Raquel, Martín, Angela, Pérez-Girón, José V., Barrús, María T., González-Carnicero, Zoe, Aguado, Andrea, Jaisser, Frederic, Briones, Ana M., Salaices, Mercedes, Alonso, María J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848177/ https://www.ncbi.nlm.nih.gov/pubmed/31712626 http://dx.doi.org/10.1038/s41598-019-52839-6 |
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