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Large-Scale Conformational Changes and Protein Function: Breaking the in silico Barrier
Large-scale conformational changes are essential to link protein structures with their function at the cell and organism scale, but have been elusive both experimentally and computationally. Over the past few years developments in cryo-electron microscopy and crystallography techniques have started...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848229/ https://www.ncbi.nlm.nih.gov/pubmed/31750315 http://dx.doi.org/10.3389/fmolb.2019.00117 |