Personalised Warfarin Dosing in Children Post-cardiac Surgery

Warfarin dosing is challenging due to a multitude of factors affecting its pharmacokinetics (PK) and pharmacodynamics (PD). A novel personalised dosing algorithm predicated on a warfarin PK/PD model and incorporating CYP2C9 and VKORC1 genotype information has been developed for children. The present...

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Detalles Bibliográficos
Autores principales: Al-Metwali, Basma Zuheir, Rivers, Peter, Goodyer, Larry, O’Hare, Linda, Young, Sanfui, Mulla, Hussain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848240/
https://www.ncbi.nlm.nih.gov/pubmed/31587090
http://dx.doi.org/10.1007/s00246-019-02215-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848240/
https://www.ncbi.nlm.nih.gov/pubmed/31587090
http://dx.doi.org/10.1007/s00246-019-02215-y

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