TRAIL-induced variation of cell signaling states provides nonheritable resistance to apoptosis

TNFα-related apoptosis-inducing ligand (TRAIL), specifically initiates programmed cell death, but often fails to eradicate all cells, making it an ineffective therapy for cancer. This fractional killing is linked to cellular variation that bulk assays cannot capture. Here, we quantify the diversity...

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Detalles Bibliográficos
Autores principales: Baskar, Reema, Fienberg, Harris G, Khair, Zumana, Favaro, Patricia, Kimmey, Sam, Green, Douglas R, Nolan, Garry P, Plevritis, Sylvia, Bendall, Sean C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848270/
https://www.ncbi.nlm.nih.gov/pubmed/31704709
http://dx.doi.org/10.26508/lsa.201900554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848270/
https://www.ncbi.nlm.nih.gov/pubmed/31704709
http://dx.doi.org/10.26508/lsa.201900554

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