Cargando…

TRAIL-induced variation of cell signaling states provides nonheritable resistance to apoptosis

TNFα-related apoptosis-inducing ligand (TRAIL), specifically initiates programmed cell death, but often fails to eradicate all cells, making it an ineffective therapy for cancer. This fractional killing is linked to cellular variation that bulk assays cannot capture. Here, we quantify the diversity...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baskar, Reema, Fienberg, Harris G, Khair, Zumana, Favaro, Patricia, Kimmey, Sam, Green, Douglas R, Nolan, Garry P, Plevritis, Sylvia, Bendall, Sean C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848270/ https://www.ncbi.nlm.nih.gov/pubmed/31704709 http://dx.doi.org/10.26508/lsa.201900554

Ejemplares similares

Parallel analysis of tri-molecular biosynthesis with cell identity and function in single cells
por: Kimmey, Samuel C., et al.
Publicado: (2019)

DRUG-NEM: Optimizing drug combinations using single-cell perturbation response to account for intratumoral heterogeneity
por: Anchang, Benedict, et al.
Publicado: (2018)

A Physiological Basis for Nonheritable Antibiotic Resistance
por: Pontes, Mauricio H., et al.
Publicado: (2020)

Nonheritable Cellular Variability Accelerates the Evolutionary Processes of Cancer
por: Frank, Steven A., et al.
Publicado: (2012)

The effects of individual nonheritable variation on fitness estimation and coexistence
por: Gomes, M. Gabriela M., et al.
Publicado: (2019)

Heterogeneous Distribution of Proton Motive Force in Nonheritable Antibiotic Resistance
por: Lee, Annie H., et al.
Publicado: (2023)

Stellate nonheritable idiopathic foveomacular retinoschisis in juveniles: case report
por: Liu, Jianan, et al.
Publicado: (2023)

Supervised dimensionality reduction for exploration of single-cell data by HSS-LDA
por: Amouzgar, Meelad, et al.
Publicado: (2022)

Mapping lung cancer epithelial-mesenchymal transition states and trajectories with single-cell resolution
por: Karacosta, Loukia G., et al.
Publicado: (2019)

Heritable and Nonheritable Rumen Bacteria Are Associated with Different Characters of Lactation Performance of Dairy Cows
por: Zang, Xin-Wei, et al.
Publicado: (2022)

Single-cell metabolic profiling of human cytotoxic T cells
por: Hartmann, Felix J., et al.
Publicado: (2020)

Extracting a Cellular Hierarchy from High-dimensional Cytometry Data with SPADE
por: Qiu, Peng, et al.
Publicado: (2011)

Draft Genome Sequences of Clinical and Nonclinical Isolates of Klebsiella spp. Exhibiting Nonheritable Tolerance toward Antimicrobial Compounds
por: Patole, Shashank, et al.
Publicado: (2017)

Unravelling human hematopoietic progenitor cell diversity through association with intrinsic regulatory factors
por: Favaro, Patricia, et al.
Publicado: (2023)

Integrating transcription-factor abundance with chromatin accessibility in human erythroid lineage commitment
por: Baskar, Reema, et al.
Publicado: (2022)

Evaluation of yield and experiences of age‐related molecular investigation for heritable and nonheritable causes of mismatch repair deficient colorectal cancer to identify Lynch syndrome
por: Vos, Janet R., et al.
Publicado: (2020)

DNA methylation at quantitative trait loci (mQTLs) varies with cell type and nonheritable factors and may improve breast cancer risk assessment
por: Herzog, Chiara, et al.
Publicado: (2023)

N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis
por: Estornes, Yann, et al.
Publicado: (2018)

TRAIL-Induced Apoptosis in TRAIL-Resistant Breast Carcinoma Through Quercetin Cotreatment
por: Manouchehri, Jasmine M, et al.
Publicado: (2018)

The Role of TRAIL in Apoptosis and Immunosurveillance in Cancer
por: Pimentel, Julio M., et al.
Publicado: (2023)

TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes
por: Staniek, Julian, et al.
Publicado: (2019)

TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress
por: Dufour, Florent, et al.
Publicado: (2016)

Targeting Death Receptor TRAIL-R2 by Chalcones for TRAIL-Induced Apoptosis in Cancer Cells
por: Szliszka, Ewelina, et al.
Publicado: (2012)

Splicing reprogramming of TRAIL/DISC-components sensitizes lung cancer cells to TRAIL-mediated apoptosis
por: Voss, Oliver H., et al.
Publicado: (2021)

TRAIL and curcumin codelivery nanoparticles enhance TRAIL-induced apoptosis through upregulation of death receptors
por: Yang, Xi, et al.
Publicado: (2017)

MIBI-TOF: A multiplexed imaging platform relates cellular phenotypes and tissue structure
por: Keren, Leeat, et al.
Publicado: (2019)

Single-cell mass cytometry reveals cross-talk between inflammation-dampening and inflammation-amplifying cells in osteoarthritic cartilage
por: Grandi, Fiorella Carla, et al.
Publicado: (2020)

TRAIL-β and TRAIL-γ: two novel splice variants of the human TNF-related apoptosis-inducing ligand (TRAIL) without apoptotic potential
por: Krieg, A, et al.
Publicado: (2003)

HTNV Sensitizes Host Toward TRAIL-Mediated Apoptosis—A Pivotal Anti-hantaviral Role of TRAIL
por: Chen, Qing-Zhou, et al.
Publicado: (2020)

The emphysematous lung is abnormally sensitive to TRAIL-mediated apoptosis
por: Morissette, Mathieu C, et al.
Publicado: (2011)

Stem cells are resistant to TRAIL receptor-mediated apoptosis
por: Szegezdi, Eva, et al.
Publicado: (2009)

The Combination of TRAIL and Isoflavones Enhances Apoptosis in Cancer Cells
por: Bronikowska, Joanna, et al.
Publicado: (2010)

Sensitizing TRAIL-resistant A549 lung cancer cells and enhancing TRAIL-induced apoptosis with the antidepressant amitriptyline
por: Zinnah, K.M.A., et al.
Publicado: (2021)

Osteoprotegerin (OPG) protects ovarian cancer cells from TRAIL-induced apoptosis but does not contribute to malignant ascites-mediated attenuation of TRAIL-induced apoptosis
por: Lane, Denis, et al.
Publicado: (2012)

Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis
por: Aldridge, Bree B, et al.
Publicado: (2011)

Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis
por: Chan, David Y. L., et al.
Publicado: (2007)

TRAIL and Taurolidine induce apoptosis and decrease proliferation in human fibrosarcoma
por: Daigeler, Adrien, et al.
Publicado: (2008)

Chalcones Enhance TRAIL-Induced Apoptosis in Prostate Cancer Cells
por: Szliszka, Ewelina, et al.
Publicado: (2009)

H-Ras regulation of TRAIL death receptor mediated apoptosis
por: Chen, Jun-Jie, et al.
Publicado: (2014)

Activation of systemic antitumor immunity via TRAIL-induced apoptosis
por: James, Britnie R., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_2j5350g2m84ae738gaodadtsvi