Ketamine and Active Ketamine Metabolites Regulate STAT3 and the Type I Interferon Pathway in Human Microglia: Molecular Mechanisms Linked to the Antidepressant Effects of Ketamine

Inflammation is an important biological process which contributes to risk for depression, in part as a result of the production of proinflammatory cytokines and of alterations in glutamatergic neurotransmission. Ketamine has anti-inflammatory properties which might contribute to its antidepressant e...

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Detalles Bibliográficos
Autores principales: Ho, Ming-Fen, Zhang, Cheng, Zhang, Lingxin, Li, Hu, Weinshilboum, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848891/
https://www.ncbi.nlm.nih.gov/pubmed/31827434
http://dx.doi.org/10.3389/fphar.2019.01302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848891/
https://www.ncbi.nlm.nih.gov/pubmed/31827434
http://dx.doi.org/10.3389/fphar.2019.01302

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