Population pharmacokinetics of pevonedistat alone or in combination with standard of care in patients with solid tumours or haematological malignancies

AIMS: A population pharmacokinetic (PK) analysis was conducted to quantify the impact of patient‐specific and concurrent medication factors on pevonedistat PK. METHODS: Data were pooled from 6 clinical studies consisting of 335 patients with solid tumours or haematological malignancies administered...

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Detalles Bibliográficos
Autores principales: Faessel, Hélène M., Mould, Diane R., Zhou, Xiaofei, Faller, Douglas V., Sedarati, Farhad, Venkatakrishnan, Karthik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848912/
https://www.ncbi.nlm.nih.gov/pubmed/31355467
http://dx.doi.org/10.1111/bcp.14078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848912/
https://www.ncbi.nlm.nih.gov/pubmed/31355467
http://dx.doi.org/10.1111/bcp.14078

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