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A Mathematical Model of Lysosomal Ion Homeostasis Points to Differential Effects of Cl(−) Transport in Ca(2+) Dynamics

The establishment and maintenance of ion gradients between the interior of lysosomes and the cytosol are crucial for numerous cellular and organismal functions. Numerous ion transport proteins ensure the required variation in luminal concentrations of the different ions along the endocytic pathway t...

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Detalles Bibliográficos
Autores principales: Astaburuaga, Rosario, Quintanar Haro, Orlando Daniel, Stauber, Tobias, Relógio, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848924/
https://www.ncbi.nlm.nih.gov/pubmed/31623161
http://dx.doi.org/10.3390/cells8101263