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Exportin-1-Dependent Nuclear Export of DEAD-box Helicase DDX3X is Central to its Role in Antiviral Immunity

DEAD-box helicase 3, X-linked (DDX3X) regulates the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR)-mediated antiviral response, but can also be a host factor contributing to the replication of viruses of significance to human health, such as human immunodeficiency virus type 1 (HIV-1). T...

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Detalles Bibliográficos
Autores principales: Heaton, Steven M., Atkinson, Sarah C., Sweeney, Melissa N., Yang, Sundy N. Y., Jans, David A., Borg, Natalie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6848931/
https://www.ncbi.nlm.nih.gov/pubmed/31575075
http://dx.doi.org/10.3390/cells8101181